K-9

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CBD ‘K-9’:  Our ‘K-9’ formula has been specially balanced with your pets in mind. This is Cannabidiol CO2 extract from industrial hemp plant based in MCT Coconut oil and hemp essential oil. This hemp essential oil with CBD provides the full therapeutic action of the hemp plant without any psychoactive THC present. We also add Rosemary antioxidant to preserve freshness.

It is pet safe and has been shown to have tremendous results with dogs! CBD has been shown to help with joint pain, anxiety, sleep, and overall pain management for animals with an endocannabinoid system (such as dogs).

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$14.90$200.87

Properties

Product Description

Our Pet Friendly CBD 'K-9' contains pure CBD CO2 extract in MCT Coconut oil. Each of our ingestable formulas contain 1mg of CBD per 2 drops.  5ml contains 102mg CBD, 15ml contains 306mg, 30ml contains 611mg CBD, and 100ml contains 2038mg CBD.

CBD K9 is a curated and specialized formulation that consists of carbon-dioxide (CO2) extracted cannabidiol extract, hemp essential oil, medium-chain triglyceride (MCT) coconut oil and rosemary antioxidant.

Studies on CBD and Canines

Dogs have a higher density of cannabinoid receptors in their brains as opposed to humans [7] and the literature has just begun to reveal studies that have been scoped to researching the effects of CBD on our canine friends. Indeed, this endocannabinoid system that is present in both humans and other mammals, is intimately involved in the regulation of neurotransmission, immunomodulation, and neuroprotection. The activation of these receptors have valuable therapeutic effects as discussed above. Dogs have 2 types of cannabinoid receptors – CB1 and CB2, which readily bind CBD compounds that are ingested or inhaled [8].

One recent study in 2018 aimed to evaluate the safety and performance of a CBD based oil on dogs with osteoarthritis – that is, a degenerative disease of the joints that can cause pain and stiffening. The researchers subjected the dogs to 2 and 8mg/kg of this oil and found an increased comfort and activity in the dogs, with no observable side-effects [9].

Another animal study in 2017 showed that activating the CB1 receptors in animals resulted in anti-convulsant effects – further supporting the neuroprotective effects of CBD extract [10].

For pet-owners who are still concerned about CBD toxicity in canines, despite recent evidence suggesting its safe and therapeutically effective effects, don’t worry! A recent study evaluated the pharmacokinetics (that is, the metabolism and excretion of a drug) of CBD administered in 3 different ways to healthy dogs – topical cream, ingested oil beads and ingested infused oil. Higher systemic concentrations of CBD were found in dogs that had consumed the CBD-infused oil orally; and even then, no observable adverse effects were noted [11].

CBD K9 – A Dog’s Best Friend

Apart from CO2-extracted cannabidiol, CBD 100 contains 3 other potent ingredients – MCT coconut oil, hemp essential oil, and rosemary antioxidant. Hemp essential oil is a complex extract which is comprised of extremely beneficial compounds such as limonene, terpinolene and caryophyllene – these have been extensively studied and confer relaxant and anti-microbial effects on the user [12].

In fact, these compounds have exhibited antimicrobial effects against “superbugs” such as Enterococcus faecium and Clostridium botulinum – an additional benefit that is extremely relevant today in view of the multi-drug resistant bacteria crisis that has emerged because of rampant antibiotic abuse [13].

While MCT coconut oil is used in our CBD K9 as a base, we would be remiss not to inform you of its health benefits. MCT coconut oil has shown systemic cardiovascular benefits in the form of its lipid-lowering effects. This is extremely relevant for patients who have documented coronary heart disease, peripheral arterial disease or even elevated levels of cholesterol (hyperlipidaemia). Even in healthy users, MCT coconut oil has shown improved metabolism and exercise endurance [14].

Most studies have been conducted in regard to the oral ingestion of MCT coconut oil[15].

Rosemary (Rosmarinus officinalis) has been widely praised since time immemorial for its antioxidant, antimicrobial, anti-inflammatory, and even anti-tumour effects! [16, 17].

For this reason alone, rosemary is the ideal candidate for a natural preservative in CBD K9. The phenolic compounds in rosemary which are antibacterial, antifungal, and antioxidant in nature, prevent the contamination, oxidation, or spoilage of the CBD K9 essential oil [16].

Why Ananda Chooses CBD CO2 Extract for Canines

At Ananda Apothecary, we guarantee the highest possible quality of cannabidiol (CBD) extract in our oils.

CO2 extraction of CBD is a form of supercritical gas extraction which differs from conventional methods of extraction, for example steam-distillation or cold-press extraction that is more common with essential oils[1]. One of the main advantages of CO2 extraction is that it allows for the extraction of active ingredients (like CBD) with a higher quality yield. This higher quality yield is attributable to the lack of thermal degradation of labile compounds as CO2 extraction is performed at a reduced temperature. Importantly, there is also a lack of light and oxygen during the process of CO2 extraction – this results in the prevention of oxidant reactions which could potentially attenuate the antioxidant potential of the cannabinoids. Yet another advantage of CO2 extraction is that the high-pressure gradient during the pressure release yields cannabinoid extracts which are free from pathogenic microbes as well as spores. This method also results in a longer shelf life of the product as compared to traditional extraction techniques [2, 3].

These cannabinoid compounds are non-intoxicating and render a plethora of benefits which range from systemic anti-inflammatory effects to anxiolysis [4]. Their antioxidant capabilities cannot be overstated – in fact, CBD has a higher antioxidant potential than Vitamins C and E. By sweeping up excess free radicals (also known as reactive oxidative species), these miraculous antioxidants inhibit the progression of, and can even prevent the onset of chronic inflammatory diseases like Multiple Sclerosis, Alzheimer’s Disease, atherosclerosis, and acne [5, 6]. 

The Ananda Apothecary CBD Formulas are different!

Many formulas make it difficult to accurately measure the amount of CBD you are using. However, because our formulas contain 1mg CBD in every two drops, the measurement is simple.

What is CBD?

If you want to really want to learn all you can, here is a peer-reviewed journal article about CBD and how it works in the body - and why certain formulations are better than others. See CBD, Nature's Most Profound Synergy Yet.

Briefly, cannabidiol (CBD) is a naturally occurring constituent of the hemp plant. It is the most abundant non-psychoactive cannabinoid. The CBD extract from which all our blends are made is a full spectrum extract of a Hemp strain of Cannabis sativa. Hemp is ideal for (CBD oil) extractions as it is naturally high in CBD and low in THC. Because of the extraction from legally grown and extracted Hemp, it is legal for shipment to all 50 states.

Our CBD extract is a full spectrum cannabinoid extract. Besides the high content of CBD, there are also present naturally occurring trace amounts of other cannabinoids, which many scientists and doctors think work in synergy to support the whole endocannabinoid system.

Most preclinical studies with cannabidiol utilize synthetic, single-molecule CBD produced by biochemical laboratories for research purposes – whereas whole plant CBD-rich extractions typically include trace amounts of THC and more than 400 other compounds, which interact synergistically to confer a holistic “entourage effect” so that the therapeutic impact of the whole plant is greater than the sum of its parts.

How is CBD made, and how do we ensure the same quality from batch to batch?

The CBD oil is extracted through supercritical CO2 extraction of 'industrial' Hemp (Cannabis sativa), which naturally has a very low concentration of THC. The raw CBD oil is then further refined to remove plant waxes and concentrate the CBD. Each batch is analyzed via High-Pressure Liquid Chromatography (HPLC) to quantify its purity, and guarantee you receive precise amounts of CBD in each and every one of our formulations.

Our testing ensures you are receiving the concentration of CBD you're paying for, and that there is no more than a trace of THC, and to ensure there are no pathogens in the oil whatsoever (yeast, mold, fungus, etc.)

Safety

Always speak to your Veterinarian before starting your pet on a new regimen. Generally speaking, we recommend using a range of drops depending on your pet's weight. We recommend starting with 3-5 mg (6-10 drops) for a medium sized dog (40-60lbs), and ramping up from there to get the desired result.
With bigger dogs, higher doses could be used, and with smaller dogs lower quantities would be a good place to start.

References

1. Diaz-Reinoso, B., et al., Supercritical CO2 extraction and purification of compounds with antioxidant activity. J Agric Food Chem, 2006. 54(7): p. 2441-69.
2. Perrut, M., Supercritical Fluid Applications: Industrial Developments and Economic Issues. Vol. 39. 2000.
3. Foster, N., et al., Processing Pharmaceutical Compounds Using Dense Gas Technology. Industrial & Engineering Chemistry Research, 2003. 42(25): p. 6476-6493.
4. Bergamaschi, M.M., et al., Safety and side effects of cannabidiol, a Cannabis sativa constituent. Curr Drug Saf, 2011. 6(4): p. 237-49.
5. Olah, A., et al., Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes. J Clin Invest, 2014. 124(9): p. 3713-24.
6. Hampson, A.J., et al., Cannabidiol and (-)Delta9-tetrahydrocannabinol are neuroprotective antioxidants. Proceedings of the National Academy of Sciences of the United States of America, 1998. 95(14): p. 8268-8273.
7. Gyles, C., Marijuana for pets? The Canadian veterinary journal = La revue veterinaire canadienne, 2016. 57(12): p. 1215-1218.
8. Chaperon, F. and M.H. Thiebot, Behavioral effects of cannabinoid agents in animals. Crit Rev Neurobiol, 1999. 13(3): p. 243-81.
9. Gamble, L.-J., et al., Pharmacokinetics, Safety, and Clinical Efficacy of Cannabidiol Treatment in Osteoarthritic Dogs. Frontiers in veterinary science, 2018. 5: p. 165-165.
10. Rosenberg, E.C., P.H. Patra, and B.J. Whalley, Therapeutic effects of cannabinoids in animal models of seizures, epilepsy, epileptogenesis, and epilepsy-related neuroprotection. Epilepsy & behavior : E&B, 2017. 70(Pt B): p. 319-327.
11. Bartner, L.R., et al., Pharmacokinetics of cannabidiol administered by 3 delivery methods at 2 different dosages to healthy dogs. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 2018. 82(3): p. 178-183.
12. Russo, E.B., Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. Br J Pharmacol, 2011. 163(7): p. 1344-64.
13. Nissen, L., et al., Characterization and antimicrobial activity of essential oils of industrial hemp varieties (Cannabis sativa L.). Fitoterapia, 2010. 81(5): p. 413-9.
14. Wang, Y., et al., Medium Chain Triglycerides enhances exercise endurance through the increased mitochondrial biogenesis and metabolism. PloS one, 2018. 13(2): p. e0191182-e0191182.
15. Lee, E.J., et al., Lipid-Lowering Effects of Medium-Chain Triglyceride-Enriched Coconut Oil in Combination with Licorice Extracts in Experimental Hyperlipidemic Mice. J Agric Food Chem, 2018. 66(40): p. 10447-10457.
16. Altinier, G., et al., Characterization of topical antiinflammatory compounds in Rosmarinus officinalis L. J Agric Food Chem, 2007. 55(5): p. 1718-23.
17. Bernardes, W.A., et al., Antibacterial activity of the essential oil from Rosmarinus officinalis and its major components against oral pathogens. Z Naturforsch C, 2010. 65(9-10): p. 588-93.

FDA Disclosure

This product is not for use by or sale to persons under the age of 18. This product should be used only as directed on the label. It should not be used if you are pregnant or nursing. Consult with a physician before use if you have a serious medical condition or use prescription medications. A Doctor's advice should be sought before using this and any supplemental dietary product. All trademarks and copyrights are property of their respective owners and are not affiliated with nor do they endorse this product. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. By using this site you agree to follow the Privacy Policy and all Terms & Conditions printed on this site. Void Where Prohibited By Law.

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